Selected publications

1. Soma T, Oie Y, Takayanagi H, Matsubara S, Yamada T, Nomura M, Yoshinaga Y, Maruyama K, Watanabe A, Takashima K, Mao Z, Quantock AJ, Hayashi R, Nishida K. Induced pluripotent stem-cell-derived corneal epithelium for transplant surgery: a single-arm, open-label, first-in-human interventional study in Japan. The Lancet. 2024; 404(10466): 1929-1939. DOI: 10.1016/S0140-6736(24)01764-1. 
2. Gaydarska H, Takashima K, Shahrier S, Raz A, Minari J. The interplay of ethics and genetic technologies in balancing the social valuation of the human genome in UNESCO declarations. European Journal of Human Genetics. 2024; 32: 725-730. DOI: 10.1038/s41431-024-01549-3. 
3. Shahrier S, Gaydarska H, Takashima K, Yoshizawa G, Minari J. A conceptual analysis of public opinion regarding genome research in Japan. Frontiers in Genetics. 2023; 14: 1170794. DOI: 10.3389/fgene.2023.1170794. 
4. Takashima K, Minari J, Chan S, Muto K. Hope for the best, but prepare for the worst: Social media posted by participants in stem cell clinical trials. Regenerative Therapy. 2023; 24: 294-297. DOI: 10.1016/j.reth.2023.07.009. 
5. Raz A, Minari J, Takashima K, Gaydarska H, Hashiloni-Dolev Y, Horn R. Old and new challenges regarding comparable and viable data sharing in population-scale genomic research. European Journal of Human Genetics. 2023; 31: 617-618. DOI: 10.1038/s41431-023-01355-3.
6. Takashima K, Soma T, Muto K, Nishida K, Minari J. Learning to listen: a complementary approach to informed consent for patients with visual impairments. Stem Cell Reports. 2022; 17: 2582-2584. DOI: 10.1016/j.stemcr.2022.10.008. 
7. Minari J, Shinomiya N, Takashima K, Yoshizawa G. Contiguous governance of synchronic and diachronic changes for the use of genome editing technologies. Frontiers in Political Science. 2022; 4: 825496. DOI: 10.3389/fpos.2022.825496.
8. Takashima K, Morrison M, Minari J. Reflection on the enactment and impact of safety laws for regenerative medicine in Japan. Stem Cell Reports. 2021; 16(6): 1425-1434. DOI: 10.1016/j.stemcr.2021.04.017.
   

   This article is selected as the cover image for the journal. For details, please visit Stem Cell Reports website

9. Minari J, Yokono M, Takashima K, Kokado M, Ida R, Hishiyama Y. Looking back: Three key lessons from 20 years of shaping Japanese genome research regulations. Journal of Human Genetics, 2021. DOI: 10.1038/s10038-021-00923-z. 
10. Chan S, Cunningham-Burley S, De Togni G, Erikainen S, Sethi N, Takashima K. Beyond binaries: dissolving the empirical/normative divide. AJOB empirical bioethics. 2020; 11(1): 17-9. DOI: 10.1080/23294515.2020.1722290.
11. Takashima K, Inoue Y, Tashiro S, Muto K. Letter in reply to: ‘Therapeutic misconception and the role of the Research Ethics Committee.’ Perinatal Medicine. 2019; 14(8). DOI: https://doi.org/10.2217/rme-2019-0041. 
12. Takashima K, Muto K. Ethical Challenges on regenerative medicine clinical research for children. Perinatal Medicine. 2018; 48(7): 783-787. (Japanese)
13. Takashima K, Muto K. Ethics surrounding regenerative medicine. Clinical Neuroscience 2018; 36(3): 373-376. (Japanese)
14. Takashima K, Inoue Y, Tashiro S, Muto K. Lessons for reviewing clinical trials using induced pluripotent stem cells: Examining the case of a first-in-human trial for age-related macular degeneration. Regenerative Medicine. 2018; 13(2): 123-128. 
15. Takashima K, Muto K. ‘Research ethics committees in Japan: Time for change, considered with the 2014 report of the advisor group on the clinical research’, Japan Pharmacological Therapeutics 2015;43(s1): s22-6. (Japanese)
16. Okamoto Y, Takahashi H, Takashima K, et al. ‘The quality of life for patients with hepatitis C who developed hepatocellular carcinoma’, The Japan Society of Nursing, 2003; 34: 252-254. (Japanese)

Book Chapter

1. Takashima K. ‘Clinical research and ethics’ in Shimoda K, et al. (ed), Clinical Research Coordinator Textbook 4th edition. The Japanese Society of Clinical Pharmacology and Therapeutics, 2021:11-12. (in Japanese)
2. Takashima K. ‘Lecture eight on the ethics of stem cell research’, in. Kamisato A and Muto K. (ed), Handbook of Research Ethics on Medical & Life Science Research, University of Tokyo Press, 2015. 101-111. (Japanese)

Other Writing

1. Yoshida M, Muto K, Takashima K, et al. ‘Overcoming the issues with the introduction of the ethics review consignment/entrustment management system’, Report by the research group on the operation of the Good Clinical Practice (GCP) to contribute to the activation of clinical trials on the project of Ministry of Health, Labour, and Welfare, 2016. (Japanese)
2. Inoue Y, Takashima K, Muto K, et al. ‘Standard operation procedure of the U.K. research ethics committees’, Report on the Ministry of Education by the research group on the U.K. Research Ethics Committee, 2015. (Japanese)
3. Takashima K. ‘Issues with the returning results of regenerative medicine research; Returning results of infectious diseases’, Record of a meeting with Dr Ellen Clayton, 2014. (Japanese)
4. Wakatsuki Y, Takashima K, et al. ‘Decision-making on medical practices for the elderly patient and the terminal patient, and evaluation and improvement of the quality of clinical practices. Observational studies on the quality evaluation of the end-of-life decision-making process’, Report on the project of Ministry of Health, Labour and Welfare, 2007.104-112. (Japanese)

Awards

• Excellent Research Awards, Department of Computational Biology and Medical Science, Graduate School of Frontier Sciences, The University of Tokyo (March, 2024)
• 15th World Congress of Bioethics, The Medard Hilhorst Poster Prize for the Asian region (2020)